Description
The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
Specifications
| Antigen | PPHLN1 |
| Classification | Polyclonal |
| Formulation | PBS with 0.03% ProClin 300; pH 7 |
| Gene Accession No. | Q8NEY8 |
| Gene Symbols | PPHLN1 |
| Immunogen | E. coli-derived Human PPHLN1 fragment |
| Quantity | 100 μL |
| Primary or Secondary | Primary |
| Target Species | Human |
| Product Type | Antibody |
| Isotype | IgG |
| Applications | Immunocytochemistry, Immunoprecipitation, Western Blot |
| Conjugate | Unconjugated |
| Gene | PPHLN1 |
| Gene Alias | CDC7 expression repressor; CR; Gastric cancer antigen Ga50; HSPC206; HSPC232; MGC48786; periphilin 1; periphilin-1; periphilin-1-like protein; Pphln1 |
| Host Species | Rabbit |
| Purification Method | Antigen affinity chromatography, Protein A |
| Regulatory Status | RUO |
| Gene ID (Entrez) | 51535 |
| Content And Storage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Form | Liquid |
Safety and Handling
WARNING: Cancer – www.P65Warnings.ca.gov
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