Description
Description
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene
Sequence: T-T-Sp-F-A
Specifications
| Antigen | GSK3B |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Dilution | Immunohistochemistry (1:50-1:100) Western Blot (1:500-1:1000) Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user. |
| Gene | GSK3B |
| Gene Symbols | GSK3B |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding S9 of human GSK3B. |
| Quantity | 100 μg |
| Primary or Secondary | Primary |
| Target Species | Human, Mouse, Rat |
| Form | Liquid |
| Applications | Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot |
| Concentration | 1 mg/mL |
| Description | Rabbit polyclonal antibody raised against synthetic phosphopeptide of GSK3B. |
| Formulation | In PBS (without mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide) |
| Gene Accession No. | P49841 |
| Host Species | Rabbit |
| Purification Method | Affinity chromatography |
| Regulatory Status | RUO |
| Gene ID (Entrez) | 2932 |
| Content And Storage | Store at -20°C.Aliquot to avoid repeated freezing and thawing. |
