Description
Histone methyltransferase. Methylates ‘Lys-79’ of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.
Specifications
Antigen | Dot1L |
Classification | Polyclonal |
Conjugate | Unconjugated |
Gene | Dot1l |
Gene Alias | A630076O07; AW907654; DKFZp586P1823; DOT1; DOT1 like histone H3K79 methyltransferase; DOT1 like histone lysine methyltransferase; DOT1L; DOT1-like histone H3 methyltransferase; DOT1-like histone H3K79 methyltransferase; DOT1-like protein; DOT1-like, histone H3 methyltransferase; DOT1-like, histone H3 methyltransferase (S. cerevisiae); H3-K79-HMTase; histone H3 methyltransferase DOT1; histone H3-K79 methyltransferase; histone methyltransferase DOT1L; histone-lysine N-methyltransferase, H3 lysine-79 specific; KIAA1814; KMT4; lysine N-methyltransferase 4; mDot1 |
Host Species | Rabbit |
Purification Method | Protein G |
Regulatory Status | RUO |
Gene ID (Entrez) | 84444 |
Content And Storage | -20°C or -80°C if preferred |
Form | Liquid |
Applications | ELISA, Immunohistochemistry (Paraffin), Western Blot |
Concentration | 3 mg/mL |
Formulation | PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4 |
Gene Accession No. | Q8TEK3 |
Gene Symbols | Dot1l |
Immunogen | Recombinant Human Histone-lysine N-methyltransferase, H3 lysine-79 specific protein (331-484AA) |
Quantity | 100 μg |
Primary or Secondary | Primary |
Target Species | Human |
Product Type | Antibody |
Isotype | IgG |
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