Description
Antibody detects endogenous levels of total CGK2.
PRKG2 (PKG2, cGKII) exhibits many cellular functions and has cAMP- and cGMP-dependent protein kinase activity. cGKII is thought to play a key role in a diverse set of physiological pathway. cGKII may mediate intestinal secretion of water and electrolytes induced by the E. coli toxin STa and the intestinal peptide guanylin. Identification of the pathway that mediates intestinal fluid secretion by E. coli. cGKII is postulated to be a molecular switch that couples the cessation of proliferation and the start of hypertrophic chondrocyte differentiation through attenuating SOX9 function.
Specifications
| Antigen | cGKII |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Gene | PRKG2 |
| Gene Alias | AW212535; cGK 2; cGK2; cGKII; cGK-II; cGMP dependent protein kinase type II; cGMP-dependent protein kinase 2; cGMP-dependent protein kinase II; EC 2.7.11.12; GDPKII; PRKG2; PRKGR2; protein kinase cGMP- dependent type 2; protein kinase, cGMP- dependent, type 2; protein kinase, cGMP- dependent, type II; protein kinase, cGMP-dependent, type II; testicular tissue protein Li 99; type II cGMP-dependent protein kinase |
| Host Species | Rabbit |
| Purification Method | Affinity chromatography |
| Regulatory Status | RUO |
| Gene ID (Entrez) | 19092, 25523, 5593 |
| Content And Storage | -20°C |
| Form | Liquid |
| Applications | Immunocytochemistry, Western Blot |
| Concentration | 1 mg/mL |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene Accession No. | Q13237, Q61410, Q64595 |
| Gene Symbols | PRKG2 |
| Immunogen | A synthesized peptide derived from human PRKG2(Accession Q13237), corresponding to amino acid residues V101-K151. |
| Quantity | 100 μL |
| Primary or Secondary | Primary |
| Target Species | Human, Mouse, Non-human Primate, Rat |
| Product Type | Antibody |
| Isotype | IgG |
Safety and Handling
WARNING: Cancer – www.P65Warnings.ca.gov
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