Description
Description
The HI10a monoclonal antibody specifically binds to CD10 which is also known as Neutral endopeptidase (NEP), Enkephalinase, Atriopeptidase, and Neprilysin. CD10 is encoded by MME (membrane metallo-endopeptidase). CD10 is a 100 kDa type II transmembrane glycoprotein that has neutral endopeptidase activity and is otherwise known as the Common Acute Lymphoblastic Leukemia Antigen (CALLA). CD10 is expressed on a wide variety of normal and neoplastic cell types. Normal cells expressing CD10 include granulocytes, bone marrow stromal cells, a subset of B-cell progenitors, germinal center B cells and fibroblasts. This cell surface metalloendopeptidase inactivates a number of signaling molecules and serves as a major regulator in the nervous, immune and other systems.
Specifications
| Antigen | CD10 |
| Classification | Monoclonal |
| Conjugate | Brilliant Violet 650 |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Immunogen | Acute CALLA Leukemia Blast Cells |
| Quantity | 100 Tests |
| Primary or Secondary | Primary |
| Content And Storage | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Applications | Flow Cytometry |
| Clone | HI10A |
| Description | MME; CALLA; EPN; NEP; neprilysin; SFE; atriopeptidase; enkephalinase |
| Host Species | Mouse |
| Purification Method | Affinity Purified |
| Regulatory Status | RUO |
| Target Species | Human |
| Isotype | IgG1 κ |
