Description
Description
The HI10a monoclonal antibody specifically binds to CD10 which is also known as Neutral endopeptidase (NEP), Enkephalinase, Atriopeptidase, and Neprilysin. CD10 is encoded by MME (membrane metallo-endopeptidase). CD10 is a 100 kDa type II transmembrane glycoprotein that has neutral endopeptidase activity and is otherwise known as the Common Acute Lymphoblastic Leukemia Antigen (CALLA). CD10 is expressed on a wide variety of normal and neoplastic cell types. Normal cells expressing CD10 include granulocytes, bone marrow stromal cells, a subset of B-cell progenitors, germinal center B cells and fibroblasts. This cell surface metalloendopeptidase inactivates a number of signaling molecules and serves as a major regulator in the nervous, immune and other systems.
Specifications
Antigen |
CD10 |
Classification |
Monoclonal |
Conjugate |
Brilliant Violet 650 |
Formulation |
Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
Immunogen |
Acute CALLA Leukemia Blast Cells |
Quantity |
100 Tests |
Primary or Secondary |
Primary |
Content And Storage |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
Applications |
Flow Cytometry |
Clone |
HI10A |
Description |
MME; CALLA; EPN; NEP; neprilysin; SFE; atriopeptidase; enkephalinase |
Host Species |
Mouse |
Purification Method |
Affinity Purified |
Regulatory Status |
RUO |
Target Species |
Human |
Isotype |
IgG1 κ |